|
|
25-hydroxyvitamin_D3 + reduced_adrenodoxin + O2 + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.18
calcidiol 1-monooxygenase
|
–
|
MK
|
|
BRENDA:
BR40512
KEGG:
R03610
MetaCyc:
CALCIDIOL-1-MONOOXYGENASE-RXN
|
|
|
|
25-hydroxyvitamin_D3 + reduced_adrenodoxin + H+ + O2 <=> secalciferol + oxidized_ferredoxin + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49598
KEGG:
R09516
MetaCyc:
RXN-12069
|
|
|
|
vitamin_D3 + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 25-hydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.22
vitamin D 1,25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR51834
KEGG:
R11458
MetaCyc:
RXN-18214
|
|
|
|
25-hydroxyvitamin_D3 + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.22
vitamin D 1,25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR51835
KEGG:
R11459
MetaCyc:
RXN-18215
|
|
|
|
vitamin_D3 + O2 + reduced_flavodoxin <=> 25-hydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR50107
KEGG:
R03611
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
1.14.15.15
cholestanetriol 26-monooxygenase
1.14.15.18
calcidiol 1-monooxygenase
|
–
–
–
|
B
|
|
BRENDA:
BS289214;
BS370277
SABIO-RK:
3392;
7072
|
|
|
|
vitamin_D3 + NADPH + O2 <=> 25-hydroxyvitamin_D3 + NADP+ + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
1.14.15.15
cholestanetriol 26-monooxygenase
1.14.15.18
calcidiol 1-monooxygenase
|
–
–
–
|
B
|
|
BRENDA:
BS402537;
BS418543
SABIO-RK:
12139
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> secalciferol + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS416192
SABIO-RK:
12063
|
|
|
|
vitamin_D3 + H2O + acceptor <=> 25-hydroxyvitamin_D3 + reduced_acceptor
|
1.17.99.e
|
–
|
|
|
MetaCyc:
RXN-21493
|
|
|
|
vitamin_D3 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 25-hydroxyvitamin_D3 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-9829
|
|
|
|
25-hydroxyvitamin_D3 + H+ + O2 <=> 25-hydroxyvitamin_D3 + H2O
|
1.14.15.18
calcidiol 1-monooxygenase
|
–
|
|
|
BRENDA:
BS436245
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D3 + NADPH + O2
|
1.14.15.18
calcidiol 1-monooxygenase
|
–
|
|
|
BRENDA:
BS413194
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 25,26,27-trinor-23-ene-vitamin_D3 + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS416193
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,25-dihydroxyvitamin_D3-26,23-lactone + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS416191
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24,25,26,27-tetranor-23-hydroxyvitamin-D3 + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS416190
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24,25-dihydroxyvitamin_D3 + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS427294
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24-oxo-25-hydroxycholecalciferol + 23(S),25-dihydroxyvitamin_D3 + secalciferol + 24-oxo-23(S),25-dihydoxyvitamin_D3 + NADP+ + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
|
BRENDA:
BS416189
|
|
|
|
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D + NADP+ + H2O
|
1.14.15.18
calcidiol 1-monooxygenase
|
–
|
|
|
BRENDA:
BS386066
|
|